News & Events
Rational Computational Design of Systems Exhibiting Strong Halogen Bonding Involving Fluorine in Bicyclic Diamine Derivatives was published in The Journal of Organic Chemistry in May 2022. DOI: doi.org/10.1021/acs.joc.2c00497
Organocatalysis Linked to Charge-Enhanced Acidity with Superelectrophilic Traits was published in ACS Catalysis in January 2022. DOI: https://doi.org/10.1021/acscatal.1c05296
Generation and reactivity of an elusive base-stabilised phosphinidene was published in Dalton Transactions in October 2021. DOI:https://doi.org/10.1039/D1DT03181C
DFT-Based Stereochemical Rationales for the Bifunctional Brønsted Acid/Base-Catalyzed Diastereodivergent and Enantioselective aza-Henry Reactions of α-Nitro Esters was published in the Journal of Organic Chemistry in October 2021. DOI: https://doi.org/10.1021/acs.joc.1c02112
Dr. Travis Dudding and Rozhin Rowshanpour were featured in the Brock News for their recent article in Nature Communications on modified sugar molecules used in medicine.
Dr. Travis Dudding was featured in the Brock News in the faculty Focus segment on his Chemistry career path.
pKa Scale for Cyclopropenium Ions with Applications in CO2 Capture was published in the Journal of Organic Chemistry in August 2021. DOI: https://doi.org/10.1021/acs.joc.1c01255
Diversity-oriented synthesis of glycomimetics was published in Communications Chemistry in June 2021. DOI: https://doi.org/10.1038/s42004-021-00520-3
Bronsted Acid Organocatalyzed Three-Component Hydroamidation Reaction of Vinyl Ethers was published in the Journal of Organic Chemistry in February 2021. DOI: https://doi.org/10.1021/acs.joc.0c03017
Azo synthesis meets molecular iodine catalysis was published in the Journal of Royal Society of Chemistry in February 2021. DOI: https://doi.org/10.1039/D1RA00369K
Dr. Travis Dudding was featured in The Brock News with an article on his partnership with Niagara Pharmaceutical Company on COVID-19 prevention!
Oxidative Rearrangement of MIDA (N-Methyliminodiacetic Acid) Boronates: Mechanistic Insights and Synthetic Applications was published in the Journal of Organic Letters in January 2021. DOI: https://doi.org/10.1021/acs.orglett.0c03823
Cooperative Noncovalent Interactions Lead to a Highly Diastereoselective Sulfonyl-Directed Fluorination of Steroidal α,β- Unsaturated Hydrazones was published in the Journal of Organic Chemistry in December 2020. DOI: https://doi.org/10.1021/acs.joc.0c02716
Trisaminocyclopropenium Cations as Small Molecule Organic Fluorophores: Design Guidelines and Bioimaging Applications was published in the Journal of Organic Chemistry in September 2020. DOI: https://doi.org/10.1021/acs.joc.0c02026
Carbonyl-Directed Aliphatic Fluorination: A Special Type of Hydrogen Atom Transfer Beats Out Norrish II was published in the Journal of the American Chemical Society in August 2020. DOI: https://doi.org/10.1021/jacs.0c07004
DFT Case Study of the Mechanism of a Metal-Free Oxygen Atom Insertion into a p-Quinone Methide C(sp3)–C(sp2) Bond was published in the Jounal of Organic Chemistry in July 2020. DOI: https://doi.org/10.1021/acs.joc.0c01371
Congratulations to Matt Guest on receiving the Spring 2020 Distinguished Graduate Student Award-Chemistry (MSc) for having the highest overall average!
Congratulations to the Dudding lab on receiving 2 NSERC Alliance Grants for research into the novel 2019 Coronavirus (COVID-19)!
Stereoselective Synthesis of N‐Propargyl Alkynes and Axial Chiral N‐Allenes with Epimeric Pyrroloimidazolone Auxiliaries was published in the Journal of the American Chemical Society in June 2020 DOI: https://doi.org/10.1002/adsc.202000574
Organofluorine Compounds in Fluorine-18 Positron Emission Tomography Imaging was published in the Research and Reviews on Healthcare in June 2020. DOI: http://dx.doi.org/10.32474/RRHOAJ.2020.05.000213
Development of an Unsymmetrical Cyclopropenimine‐Guanidine Platform for Accessing Strongly Basic Proton Sponges and Boron‐Difluoride Diaminonaphthalene Fluorophores was published in Chemistry - A European Journal in May 2020 as a selected "Hot Paper" DOI: https://doi.org/10.1002/chem.202001227
Site-Selective Photochemical Fluorination of Ketals: Unanticipated Outcomes in Selectivity and Stability was published in the Journal of the American Chemical Society in February 2020 as a selected "featured article."
DOI: https://pubs.acs.org/doi/abs/10.1021/acs.joc.9b03047
Congratulations to Matt Guest on earning a Masters of Science Degree!
Site-Selective Photochemical Fluorination of Ketals: Unanticipated Outcomes in Selectivity and Stability was published in the Journal of the American Chemical Society in February 2020. DOI: https://doi.org/10.1021/acs.joc.9b03047
Stereoelectronic and Resonance Effects on the Rate of Ring Opening of N-Cyclopropyl-Based Single Electron Transfer Probes was published in the Journal of the American Chemical Society in January 2020. DOI: https://pubs.acs.org/doi/10.1021/jacs.9b12617
Mechanistic Insight Towards Understanding the Role of Charge in Thiourea Organocatalysis was published in the Journal of Organic Chemistry. DOI: https://doi.org/10.1021/acs.joc.9b02682
Discovery and Mechanistic Study of a Totally Organic C(aryl)-C(alkyl) Oxygen Insertion Reaction was published in the Journal of Organic Chemistry in October 2019. DOI: https://pubs.acs.org/doi/abs/10.1021/acs.joc.9b02238
Congratulations to Richard Le Sueur on earning a Masters of Science Degree!
Congratulations to Hayden Foy on earning a Masters of Science Degree!
Ligand Effect in Alkali Metal‐Catalyzed Transfer Hydrogenation of Ketones was published in Chemistry - A European Journal in July 2019. DOI: https://doi.org/10.1002/chem.201902240
Competitive hydrogen bonding of cyclopropenium ions: Implications of an anion switch was published in a Tetrahedron Letters in July 2019. DOI: https://doi.org/10.1016/j.tetlet.2019.07.019
Organocatalysis Linked to Charge-Enhanced Acidity with Superelectrophilic Traits was published in ACS Catalysis in January 2022. DOI: https://doi.org/10.1021/acscatal.1c05296
Generation and reactivity of an elusive base-stabilised phosphinidene was published in Dalton Transactions in October 2021. DOI:https://doi.org/10.1039/D1DT03181C
DFT-Based Stereochemical Rationales for the Bifunctional Brønsted Acid/Base-Catalyzed Diastereodivergent and Enantioselective aza-Henry Reactions of α-Nitro Esters was published in the Journal of Organic Chemistry in October 2021. DOI: https://doi.org/10.1021/acs.joc.1c02112
Dr. Travis Dudding and Rozhin Rowshanpour were featured in the Brock News for their recent article in Nature Communications on modified sugar molecules used in medicine.
Dr. Travis Dudding was featured in the Brock News in the faculty Focus segment on his Chemistry career path.
pKa Scale for Cyclopropenium Ions with Applications in CO2 Capture was published in the Journal of Organic Chemistry in August 2021. DOI: https://doi.org/10.1021/acs.joc.1c01255
Diversity-oriented synthesis of glycomimetics was published in Communications Chemistry in June 2021. DOI: https://doi.org/10.1038/s42004-021-00520-3
Bronsted Acid Organocatalyzed Three-Component Hydroamidation Reaction of Vinyl Ethers was published in the Journal of Organic Chemistry in February 2021. DOI: https://doi.org/10.1021/acs.joc.0c03017
Azo synthesis meets molecular iodine catalysis was published in the Journal of Royal Society of Chemistry in February 2021. DOI: https://doi.org/10.1039/D1RA00369K
Dr. Travis Dudding was featured in The Brock News with an article on his partnership with Niagara Pharmaceutical Company on COVID-19 prevention!
Oxidative Rearrangement of MIDA (N-Methyliminodiacetic Acid) Boronates: Mechanistic Insights and Synthetic Applications was published in the Journal of Organic Letters in January 2021. DOI: https://doi.org/10.1021/acs.orglett.0c03823
Cooperative Noncovalent Interactions Lead to a Highly Diastereoselective Sulfonyl-Directed Fluorination of Steroidal α,β- Unsaturated Hydrazones was published in the Journal of Organic Chemistry in December 2020. DOI: https://doi.org/10.1021/acs.joc.0c02716
Trisaminocyclopropenium Cations as Small Molecule Organic Fluorophores: Design Guidelines and Bioimaging Applications was published in the Journal of Organic Chemistry in September 2020. DOI: https://doi.org/10.1021/acs.joc.0c02026
Carbonyl-Directed Aliphatic Fluorination: A Special Type of Hydrogen Atom Transfer Beats Out Norrish II was published in the Journal of the American Chemical Society in August 2020. DOI: https://doi.org/10.1021/jacs.0c07004
DFT Case Study of the Mechanism of a Metal-Free Oxygen Atom Insertion into a p-Quinone Methide C(sp3)–C(sp2) Bond was published in the Jounal of Organic Chemistry in July 2020. DOI: https://doi.org/10.1021/acs.joc.0c01371
Congratulations to Matt Guest on receiving the Spring 2020 Distinguished Graduate Student Award-Chemistry (MSc) for having the highest overall average!
Congratulations to the Dudding lab on receiving 2 NSERC Alliance Grants for research into the novel 2019 Coronavirus (COVID-19)!
Stereoselective Synthesis of N‐Propargyl Alkynes and Axial Chiral N‐Allenes with Epimeric Pyrroloimidazolone Auxiliaries was published in the Journal of the American Chemical Society in June 2020 DOI: https://doi.org/10.1002/adsc.202000574
Organofluorine Compounds in Fluorine-18 Positron Emission Tomography Imaging was published in the Research and Reviews on Healthcare in June 2020. DOI: http://dx.doi.org/10.32474/RRHOAJ.2020.05.000213
Development of an Unsymmetrical Cyclopropenimine‐Guanidine Platform for Accessing Strongly Basic Proton Sponges and Boron‐Difluoride Diaminonaphthalene Fluorophores was published in Chemistry - A European Journal in May 2020 as a selected "Hot Paper" DOI: https://doi.org/10.1002/chem.202001227
Site-Selective Photochemical Fluorination of Ketals: Unanticipated Outcomes in Selectivity and Stability was published in the Journal of the American Chemical Society in February 2020 as a selected "featured article."
DOI: https://pubs.acs.org/doi/abs/10.1021/acs.joc.9b03047
Congratulations to Matt Guest on earning a Masters of Science Degree!
Site-Selective Photochemical Fluorination of Ketals: Unanticipated Outcomes in Selectivity and Stability was published in the Journal of the American Chemical Society in February 2020. DOI: https://doi.org/10.1021/acs.joc.9b03047
Stereoelectronic and Resonance Effects on the Rate of Ring Opening of N-Cyclopropyl-Based Single Electron Transfer Probes was published in the Journal of the American Chemical Society in January 2020. DOI: https://pubs.acs.org/doi/10.1021/jacs.9b12617
Mechanistic Insight Towards Understanding the Role of Charge in Thiourea Organocatalysis was published in the Journal of Organic Chemistry. DOI: https://doi.org/10.1021/acs.joc.9b02682
Discovery and Mechanistic Study of a Totally Organic C(aryl)-C(alkyl) Oxygen Insertion Reaction was published in the Journal of Organic Chemistry in October 2019. DOI: https://pubs.acs.org/doi/abs/10.1021/acs.joc.9b02238
Congratulations to Richard Le Sueur on earning a Masters of Science Degree!
Congratulations to Hayden Foy on earning a Masters of Science Degree!
Ligand Effect in Alkali Metal‐Catalyzed Transfer Hydrogenation of Ketones was published in Chemistry - A European Journal in July 2019. DOI: https://doi.org/10.1002/chem.201902240
Competitive hydrogen bonding of cyclopropenium ions: Implications of an anion switch was published in a Tetrahedron Letters in July 2019. DOI: https://doi.org/10.1016/j.tetlet.2019.07.019
Matt Guest was featured by Brock University to showcase his research and his time at Brock!
brocku.ca/graduate-studies/student-profiles/matt-guest/
brocku.ca/graduate-studies/student-profiles/matt-guest/
The Dudding Group traveled to the Canadian Chemistry Conference and Exhibition in Quebec City in June 2019 to present their research.
Congratulations to Ivor Smajlagic on receiving a Queen Elizabeth II Scholarship!
Congratulations to Ivor Smajlagic on receiving a Queen Elizabeth II Scholarship!
Congratulations to Matt Guest for winning an award for his poster presentation at the 37th annual Graduate student Symposium at UB!
The Dudding Group traveled to the University at Buffalo to attend the 37th annual Graduate Student Symposium and present their current research.
The article, Direct Observation and Analysis of the Halo-Amino-Nitro Alkane Functional Group, was featured in a Chem Preview. DOI: https://doi.org/10.1016/j.chempr.2019.04.014
The Dudding group presented their research at the Mapping New Knowledge Conference at Brock University.
Congratulations to Matt Guest on receiving the Ontario Graduate Scholarship!
Rozhin Rowshanpour presented her work on the Dicyclopropenylidene-Ag(I) Complex at the 47th Southern Ontario Undergraduate Student Chemistry Conference
A mechanistic study of oxygen atom transfer from N-sulfonyloxaziridine to enolates was published in Tetrahedron in April 2019. DOI: https://doi.org/10.1016/j.tet.2019.02.051
Direct Observation and Analysis of the Halo-Amino-Nitro Alkane Functional Group was published in Chem in March 2019. DOI: https://doi.org/10.1016/j.chempr.2019.03.001
Selective Aerobic Oxidation of Benzylic Alcohols Catalyzed by a Dicyclopropenylidene-Ag(I) Complex was published in the Journal of Organic Chemistry in March 2019. DOI: 10.1021/acs.joc.9b00624
Dr. Travis Dudding was an invited speaker at the University at Buffalo in March 2019!
Dr. Travis Dudding was selected as a Guest Editor for a special issue in Catalysts entitled, "Exploring Hydrogen Bond and Bronsted Acid Catalysis".
The Dudding Group traveled to the 29th Quebec-Ontario Mini-Symposium for Synthetic and Bioorganic Chemistry at York University to present their research.
Cyclopropenium Enhanced Thiourea Catalysis manuscript was publish in the Journal of Organic Chemistry in October 2018. DOI: 10.1021/acs.joc.8b02321
Synthesis of α-Borylated Ketones by Regioselective Wacker Oxidation of Alkenylboronates manuscript was published in Organic Letters in August 2018. DOI: 10.1021/acs.orglett.8b02234
Dr. Travis Dudding was featured in a Chemistry World News Article about his recent Nature article with Dr. Andrei Yudin.
Amine hemilability enables boron to mechanistically resemble either hydride or proton manuscript was accepted in Nature Chemistry in July 2018. DOI: https://doi.org/10.1038/s41557-018-0097-5
A Mechanistic Model for the Aziridine Aldehyde-driven Macrocyclization of Peptides manuscript was accepted in The Journal of Organic Chemistry in July 2018. DOI: 10.1021/acs.joc.8b01198
The Dudding group was featured in The Brock News with an article on their recent collaboration with Atlantic Biodiesel.
Dr. Dudding was an invited speaker at the University of Saskatchewan in June 2018!
Dr. Travis Dudding was promoted to Full Professor of Chemistry at Brock University!
The Fluorescence of Cyclopropenium Ion Derivatives manuscript was accepted in The Journal of Organic Chemistry in May 2018. DOI: 10.1021/acs.joc.8b00770
The Dudding Group traveled to the University at Buffalo to present their research at the Graduate Student Symposium!
Dr. Dudding was an invited speaker at Vanderbilt University on April 30th, 2018.
Manuscript accepted in Tetrahedron in April 2018. DOI: https://doi.org/10.1016/j.tet.2018.04.083
Dr. Dudding was an invited speaker at the Royal Military College of Canada on April 11th, 2018.
Manuscript accepted in the Journal of Organic Chemistry in April 2018. DOI: 10.1021/acs.joc.8b00060
Congratulations to Matt Guest and Hayden Foy on receiving Ontario Graduate Scholarship Awards.
Manuscript accepted in ACS Catalysis in November 2017. DOI: 10.1021/acscatal.7b02811
Manuscript accepted in the Journal of Organic Chemistry in December 2016. DOI: 10.1021/acs.joc.6b02733
Dr. Dudding hosted the 44th annual Ontario-Quebec Physical Organic Chemistry Mini Symposium at Brock University on November 4-6, 2016.
Manuscript accepted in the Canadian Journal of Chemistry in August 2016. DOI: https://doi.org/10.1139/cjc-2016-0327
Manuscript accepted in Dalton Transactions in May 2016. DOI: 10.1039/C6DT02001A
Matt Guest and Richard Le Sueur join the Dudding group.
Congratulations Dr. Lee Belding on earning a Ph.D.!
Katie Dempsey and Ivor Smajlagic join the Dudding group.
Congratulation Peter Stoyanov on earning an M.Sc.!
Congratulations Dr. Maryamdokht (Nazanine) Taimoory on earning a Ph.D.!
Congratulations Shahab Movahedi on earning an M.Sc.!
Manuscript accepted in Tetrahedron: Asymmetry DOI: 10.1016/j.tetasy.2015.04.001
The Dudding lab gets in the Brock News again!
The Dudding lab gets in the Brock News!
Manuscript accepted in ACS Catalysis DOI: 10.1021/cs501062u
Manuscript accepted in JOC DOI: 10.1021/jo501242r
Congratulations to Roya and Nazanin for winning best poster presentation at POMs 2014!
Congratulations to Lee for winning best oral presentation at POMs 2014!
Peter Stoyanov joins the Dudding group.
Manuscript accepted in JACS DOI: 10.1021/ja505592h
Congratulations to Roya Mirabdolbaghi on becoming the first student to graduate with a Ph.D. from the Dudding group!
Congratulations to David Hurem on successfully defending his M.Sc. thesis!
Congratulations to Mohamad Hassan on successfully defending his M.Sc. thesis!
Manuscript accepted in Org. Lett. DOI: 10.1021/ol501068f
Manuscript accepted in RSC Advances. DOI: 10.1039/C4RA01542H
Manuscript accepted in Angewandte Chemie International Edition. DOI: 110.1002/anie.20130942110.1039/C6DT02001A
The Dudding group presented their research at the Mapping New Knowledge Conference at Brock University.
Congratulations to Matt Guest on receiving the Ontario Graduate Scholarship!
Rozhin Rowshanpour presented her work on the Dicyclopropenylidene-Ag(I) Complex at the 47th Southern Ontario Undergraduate Student Chemistry Conference
A mechanistic study of oxygen atom transfer from N-sulfonyloxaziridine to enolates was published in Tetrahedron in April 2019. DOI: https://doi.org/10.1016/j.tet.2019.02.051
Direct Observation and Analysis of the Halo-Amino-Nitro Alkane Functional Group was published in Chem in March 2019. DOI: https://doi.org/10.1016/j.chempr.2019.03.001
Selective Aerobic Oxidation of Benzylic Alcohols Catalyzed by a Dicyclopropenylidene-Ag(I) Complex was published in the Journal of Organic Chemistry in March 2019. DOI: 10.1021/acs.joc.9b00624
Dr. Travis Dudding was an invited speaker at the University at Buffalo in March 2019!
Dr. Travis Dudding was selected as a Guest Editor for a special issue in Catalysts entitled, "Exploring Hydrogen Bond and Bronsted Acid Catalysis".
The Dudding Group traveled to the 29th Quebec-Ontario Mini-Symposium for Synthetic and Bioorganic Chemistry at York University to present their research.
Cyclopropenium Enhanced Thiourea Catalysis manuscript was publish in the Journal of Organic Chemistry in October 2018. DOI: 10.1021/acs.joc.8b02321
Synthesis of α-Borylated Ketones by Regioselective Wacker Oxidation of Alkenylboronates manuscript was published in Organic Letters in August 2018. DOI: 10.1021/acs.orglett.8b02234
Dr. Travis Dudding was featured in a Chemistry World News Article about his recent Nature article with Dr. Andrei Yudin.
Amine hemilability enables boron to mechanistically resemble either hydride or proton manuscript was accepted in Nature Chemistry in July 2018. DOI: https://doi.org/10.1038/s41557-018-0097-5
A Mechanistic Model for the Aziridine Aldehyde-driven Macrocyclization of Peptides manuscript was accepted in The Journal of Organic Chemistry in July 2018. DOI: 10.1021/acs.joc.8b01198
The Dudding group was featured in The Brock News with an article on their recent collaboration with Atlantic Biodiesel.
Dr. Dudding was an invited speaker at the University of Saskatchewan in June 2018!
Dr. Travis Dudding was promoted to Full Professor of Chemistry at Brock University!
The Fluorescence of Cyclopropenium Ion Derivatives manuscript was accepted in The Journal of Organic Chemistry in May 2018. DOI: 10.1021/acs.joc.8b00770
The Dudding Group traveled to the University at Buffalo to present their research at the Graduate Student Symposium!
Dr. Dudding was an invited speaker at Vanderbilt University on April 30th, 2018.
Manuscript accepted in Tetrahedron in April 2018. DOI: https://doi.org/10.1016/j.tet.2018.04.083
Dr. Dudding was an invited speaker at the Royal Military College of Canada on April 11th, 2018.
Manuscript accepted in the Journal of Organic Chemistry in April 2018. DOI: 10.1021/acs.joc.8b00060
Congratulations to Matt Guest and Hayden Foy on receiving Ontario Graduate Scholarship Awards.
Manuscript accepted in ACS Catalysis in November 2017. DOI: 10.1021/acscatal.7b02811
Manuscript accepted in the Journal of Organic Chemistry in December 2016. DOI: 10.1021/acs.joc.6b02733
Dr. Dudding hosted the 44th annual Ontario-Quebec Physical Organic Chemistry Mini Symposium at Brock University on November 4-6, 2016.
Manuscript accepted in the Canadian Journal of Chemistry in August 2016. DOI: https://doi.org/10.1139/cjc-2016-0327
Manuscript accepted in Dalton Transactions in May 2016. DOI: 10.1039/C6DT02001A
Matt Guest and Richard Le Sueur join the Dudding group.
Congratulations Dr. Lee Belding on earning a Ph.D.!
Katie Dempsey and Ivor Smajlagic join the Dudding group.
Congratulation Peter Stoyanov on earning an M.Sc.!
Congratulations Dr. Maryamdokht (Nazanine) Taimoory on earning a Ph.D.!
Congratulations Shahab Movahedi on earning an M.Sc.!
Manuscript accepted in Tetrahedron: Asymmetry DOI: 10.1016/j.tetasy.2015.04.001
The Dudding lab gets in the Brock News again!
The Dudding lab gets in the Brock News!
Manuscript accepted in ACS Catalysis DOI: 10.1021/cs501062u
Manuscript accepted in JOC DOI: 10.1021/jo501242r
Congratulations to Roya and Nazanin for winning best poster presentation at POMs 2014!
Congratulations to Lee for winning best oral presentation at POMs 2014!
Peter Stoyanov joins the Dudding group.
Manuscript accepted in JACS DOI: 10.1021/ja505592h
Congratulations to Roya Mirabdolbaghi on becoming the first student to graduate with a Ph.D. from the Dudding group!
Congratulations to David Hurem on successfully defending his M.Sc. thesis!
Congratulations to Mohamad Hassan on successfully defending his M.Sc. thesis!
Manuscript accepted in Org. Lett. DOI: 10.1021/ol501068f
Manuscript accepted in RSC Advances. DOI: 10.1039/C4RA01542H
Manuscript accepted in Angewandte Chemie International Edition. DOI: 110.1002/anie.20130942110.1039/C6DT02001A
